top of page



Targeting Paediatric Diffuse Midline Glioma Using Cell Therapy
A further grant has been made to Dr Ashley Vardon, NIHR Academic Clinical Lecturer, Institute of Cancer and Genomic sciences, University of Birmingham. DIPG Neurospheres - Image: University of Birmingham Recently, CAR T-cell therapy has emerged as a treatment option for diffuse midline glioma (DMG) including diffuse intrinsic pontine glioma (DIPG). After treatment some patients with H3 K27M-mutated DMG benefited from clinical and neurological improvements, and reduced tumour
Jun 124 min read


PhD Studentship for innovative radiotherapy treatments in diffuse midline glioma (DMG)
This research project 'Exploiting the potential of protons and high-LET radiation in Diffuse Midline Glioma' aims to investigate new...
Sep 16, 20254 min read


FDA Approves Modeyso/ONC201 for Patients with Diffuse Midline Glioma
J azz Pharmaceuticals Announces U.S. FDA Approval of Modeyso™ (dordaviprone) as the First and Only Treatment for Recurrent H3 K27M-mutant...
Aug 7, 20253 min read


Engineering immune cell therapy for GD2-Positive Paediatric Solid Tumours
A small project grant to generate pre-clinical data has been made to: Dr Ashley Vardon, NIHR Academic Clinical Lecturer, Institute of...
Jun 25, 20252 min read


A consensus to accelerate drug development for DIPG/DMG
The Thirteenth Paediatric Strategy Forum focused on finding better treatments for children and young people with diffuse midline glioma...
Jun 18, 20253 min read


Second CAR-T study now open and recruiting at GOSH
CAR-T study targeting IL-13RA2 for paediatric-type diffuse high-grade gliomas including diffuse midline glioma Dr. Karin Straathof:...
Mar 21, 20252 min read


CAR-T cell therapy fights DIPG in Stanford Medicine trial
Some encouraging and very inspiring news from the Monje lab and CAR-T cell therapy trials at Stanford Medicine. Photo : Stanford News....
Nov 14, 20242 min read


Abbie’s Army Joins DIPG/DMG Collaborative as Leadership Partners
Abbie’s Army has joined the DIPG/DMG Collaborative as Leadership Partners
Sep 9, 20242 min read
bottom of page
